The Pan Lymphoma Cocktail (LCA+CD20+CD3+CD43) Antibody from BIOCARE MEDICAL is a Mouse Monoclonal antibody. This antibody recognizes Human antigen. The Pan Lymphoma Cocktail (LCA+CD20+CD3+CD43) Antibody has been validated for the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen.
Description
Pan Lymphoma Cocktail (LCA CD20 CD3 CD43) are specific leukocyte markers used in the identification and assessment of lymphoid neoplasms. This combination of antibodies offers a marker for the identification of a variety of leukocytes. CD45 also known as leucocyte common antigen (LCA), is expressed on hematopoietic cell lines, but absent on non-hematopoietic cell lines and non-hematopoietic tissues. CD43 is involved in activation of T-cells, B-cells, NK-cells and monocytes. CD3 antigen is a specific marker for T-cells and is present in T-cell neoplasms, but absent in B-cells. CD20 expression is restricted to normal and neoplastic B-cells, but absent from other leukocytes and tissues